Upstream Bio valued at $1.1 bln in stellar debut as healthcare IPOs heat up
Upstream stock rises 26.5% above IPO price
Drug developer valued at $1.1 bln at open
Healthcare sector leads US IPO market in 2024
Adds background throughout, analyst comments in paragraphs 8,11,12, graphic
By Arasu Kannagi Basil
Oct 11 (Reuters) -Shares of Upstream Bio UPB.O opened 26.5% above the initial public offering price in their Nasdaq debut on Friday, valuing the drug developer at $1.05 billion.
The robust debut adds to the momentum building up in the biotech sector, which saw strong investor appetite for a clutch of drug developers when they listed on the stock exchange last month.
Separately, Kaiser Permanente-backed drug developer CAMP4 Therapeutics CAMP.O and TPG-backed medical device maker CeriBell CBLL.O also rose 1.5% and 36.8%, respectively, in their debuts on Friday.
Shares of Upstream, which is developing treatments for some respiratory disorders, opened at $21.50 apiece, above the IPO price of $17.
The company raised $255 million by selling 15 million shares, 20% more than initially planned, at the top end of its marketed range of $15 and $17 each.
The Waltham, Massachusetts-based company is currently testing its lead experimental candidate, verekitug, for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), a condition characterized by benign growths that cause pain and stuffiness, in mid-stage trials.
Upstream expects to report data from the study of CRSwNP in the second half of 2025 and severe asthma in the second half of 2026.
"The company's claims of having a potential best-in-class drug for severe asthma as well as plans to explore the drug for chronic obstructive pulmonary disease, another highly prevalent and debilitating condition affecting millions worldwide, are causing investors to prick up their ears," said IPOX research analyst Lukas Muehlbauer.
HEALTHCARE SECTOR LEADS U.S. IPOS
U.S. healthcare IPOs have raised a combined $6.6 billion in 2024, the highest year-to-date total since 2021, according to data compiled by LSEG.
They account for 23% of the total IPO proceeds of $29.2 billion raised on U.S. exchanges this year, more than any other sector.
"Investor appetite is coming back as successful recent debuts show that healthcare firms can deliver strong value," Muehlbauer said.
"If this momentum holds, we could see continued strength in the biotech IPO market heading into 2025."
US IPO proceeds by industry sectors in 2024 https://reut.rs/3NmRLfz
Reporting by Arasu Kannagi Basil in Bengaluru; Editing by Shilpi Majumdar
免责声明: XM Group仅提供在线交易平台的执行服务和访问权限，并允许个人查看和/或使用网站或网站所提供的内容，但无意进行任何更改或扩展，也不会更改或扩展其服务和访问权限。所有访问和使用权限，将受下列条款与条例约束：(i) 条款与条例；(ii) 风险提示；以及(iii) 完整免责声明。请注意，网站所提供的所有讯息，仅限一般资讯用途。此外，XM所有在线交易平台的内容并不构成，也不能被用于任何未经授权的金融市场交易邀约和/或邀请。金融市场交易对于您的投资资本含有重大风险。
所有在线交易平台所发布的资料，仅适用于教育/资讯类用途，不包含也不应被视为用于金融、投资税或交易相关咨询和建议，或是交易价格纪录，或是任何金融商品或非应邀途径的金融相关优惠的交易邀约或邀请。
本网站上由XM和第三方供应商所提供的所有内容，包括意见、新闻、研究、分析、价格、其他资讯和第三方网站链接，皆保持不变，并作为一般市场评论所提供，而非投资性建议。所有在线交易平台所发布的资料，仅适用于教育/资讯类用途，不包含也不应被视为适用于金融、投资税或交易相关咨询和建议，或是交易价格纪录，或是任何金融商品或非应邀途径的金融相关优惠的交易邀约或邀请。请确保您已阅读并完全理解，XM非独立投资研究提示和风险提示相关资讯，更多详情请点击 这里。
